Lupus erythematosus

Last Updated: 2020-06-19

Author(s): -

  • Cazenave und Schedel 1833.
  • Kaposi 1872.
  • Leloir 1890.

Lupus erythematosus, LE, erythematosus, butterfly lichen, Leloir disease. 

  • Autoimmune disease of the skin and multiple internal organs.
  • Classification
    • Systemic lupus erythematosus (SLE).
    • Cutaneous lupus erythematosus (CLE).
    • Acute cutaneous lupus erythematosus (ACLE).
    • Subacute cutaneous lupus erythematosus (SCLE).
    • Intermittent cutaneous LE (ICLE).
    • Chronic cutaneous lupus erythematodes (CCLE, subtype including discoid lupus erythematodes).
  • Frequency summit: 20. - 40. Years of life...
  • F:M = 3:1.
  • The prevalence of cutaneous LE is 3 times higher than that of SLE. 
  • Cutaneous lupus erythematosus (CLE) 
    • Acute-cutaneous lupus erythematosus (ACLE) 
      • Localized ACLE.
      • Generalized ACLE.
    • Subacute Cutaneous Lupus erythematosus (SCLE) 
      • Annular SCLE.
      • Papulosquamous SCLE.
    • Intermittent Cutaneous LE       
      • Lupus erythematodes tumidus.
    • Chronic Cutaneous Lupus erythematodes (CCLE) 
      • Discoid lupus erythematosus.
      • Localized DLE
      • Generalized DLE.
    • Mucosal DLE.
      • Oral DLE.
      • Conjunctival DLE.
    • Lupus erythematodes verrucosus (hypertrophicus).
    • Lupus erythematodes profundus (lupus erythematodes-panniculitis).
  • Special forms
    • Rowell's syndrome.
    • Chilblain lupus.
    • Drug-induced lupus erythematosus.