Q fever

Last Updated: 2019-08-27

Author(s): -

Holbroock 1937.

Rickettsiosis caused by Rickettsia burneti.

  • Occurring all over the world.
  • Farmers are special.
  • Pathogen: Rickettsia burneti.
  • Infection occurs through inhalation of sheep tick excrement. Further the wool, milk or even the meat can be contaminated.
  • Transmission from person to person is extremely rare.
  • In the area of the inoculation site a partly ulcerated, possibly encrusted papule appears.
  • Locoregional lymph nodeadenopathy.
  • Febrile temperatures.
  • Maculopapular exanthema (initial at wrists and ankles).
  • Atypical pneumonia, conjunctivitis, cough.
  • Kidney, liver and CNS may be involved.
  • If necessary, intensive medical measures and transfer to the intensive care unit.
  • Control of vital parameters, fluid balance, electrolytes and protein replacement.

     

    Topical therapy

  • Loxazole Lot. 1% (reapply after 1 and 2 weeks).
  • Permethrin 5% in e.g.: Excipial U Lipolotio.
  • Prioderm® Shampoo (reapply after 1 and 2 weeks).
  • Paranix® Sprax (Dimeticon), application time: 15 min., if necessary repeat after 7 days.
  • Lausweg® foam solution, contact time: 15 min. Repeat after 7 and 14 days.
  • Rausch Laus stop® cream, application time: 20 min., repetition after 7 and 14 days.

     

    Systemic therapy

  • Doxycycline p.o. 100 mg 2x daily for 8-10 days.
  • Alternative: Ciprofloxacin p.o. 500 mg 2x daily.
  • In pronounced cases intravenously glucocorticoids 100 mg/d for 2-3 days if necessary.
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  2. Frangoulidis, D. and S.F. Fischer, [Q fever]. Dtsch Med Wochenschr, 2015. 140(16): p. 1206-8.
  3. Schneeberger, P.M., et al., Q fever in the Netherlands - 2007-2010: what we learned from the largest outbreak ever. Med Mal Infect, 2014. 44(8): p. 339-53.
  4. Bielawska-Drozd, A., et al., Q fever--selected issues. Ann Agric Environ Med, 2013. 20(2): p. 222-32.
  5. Kersh, G.J., Antimicrobial therapies for Q fever. Expert Rev Anti Infect Ther, 2013. 11(11): p. 1207-14.