Rubeosis faciei

Last Updated: 2019-08-27

Author(s): -

Erythema perstans faciei, erythema faciale perstans, erythema faciale persistens, persistent facial flushing, constitutional face mask. 

Harmless, symmetrical, butterfly-shaped cheek redness

Women > Men

  • Butterfly-shaped, erythematous, slightly scaly, chronic, blurred redness, without involvement of the perioral region.
  • Associations:
    • Keratosis pilaris
    • Keratosis pilaris syndrome
    • Ulerythema ophryogenes
  • Medical history
  • Clinic

Self-limiting. Often declining in old age.

  • Brimonidine Tartrate (Mirvaso®)
  • IPL treatment
  • Beta blocker on evidence that rubor-e-pudore was a differential.
  1. Namazi, M.R., J.L. Jorizzo, and M.K. Fallahzadeh, Rubeosis faciei diabeticorum: a common, but often unnoticed, clinical manifestation of diabetes mellitus. ScientificWorldJournal, 2010. 10: p. 70-1.
  2. Demirseren, D.D., et al., Relationship between skin diseases and extracutaneous complications of diabetes mellitus: clinical analysis of 750 patients. Am J Clin Dermatol, 2014. 15(1): p. 65-70.
  3. Sehgal, V.N., et al., Noninsulin-dependent, type II diabetes mellitus-related dermatoses: part II. Skinmed, 2011. 9(5): p. 302-8.
  4. Pavlovic, M.D., et al., The prevalence of cutaneous manifestations in young patients with type 1 diabetes. Diabetes Care, 2007. 30(8): p. 1964-7.
  5. Borkenstein, M. and M. Haidvogl, [Dimenhydrinate poisoning in childhood (author's transl)]. Padiatr Padol, 1978. 13(2): p. 201-4.