Primär kutanes diffuses grosszelliges B-Zell-Lymphom (isolierte Herde oder gruppierte Herde)
Zuletzt aktualisiert: 2022-11-16
Autor(en): -
ICD11: 2A81.A
Zuletzt aktualisiert: 2022-11-16
Autor(en): -
ICD11: 2A81.A
Primär kutanes diffus-grosszelliges B-Zell-Lymphom, leg type.
Zentroblastär und immunoblastär differenziertes, primär kutanes B-Zell Lymphom.
Assoziation: Rheumatoide Polyarthritis, chronische Lymphödemen
Meist an den Unterschenkeln auftretende erythematös, derb palpable, teils ulzerierte Knoten.
5-Jahresüberlebensrate: 40%
Dieser Inhalt steht nur registrierten Nutzer:innen zur Verfügung
Ausdehnung |
Therapie der ersten Wahl |
Therapie der zweiten Wahl |
Isolierte Herde oder gruppierte Herde |
Radiotherapie und/oder R-CHOP Exzision |
|
Multiple Herde |
R-CHOP |
Doxorubicin oder Gemcitabin, ggf. in Kombination mit Rituximab |
Quelle: Stadler, R., et al., Short German guidelines: cutaneous lymphomas. J Dtsch Dermatol Ges, 2008. 6 Suppl 1: p. S25-31.
Bei Therapieresistenz:
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