Angular cheilitis

Last Updated: 2020-06-25

Author(s): Navarini

Perlèche, foul corners, angular cheilitis, angular stomatitis.

Frequent inflammation of the corners of the mouth or the commissures of the lips.

Frequent, especially in the case of the formation of a moist chamber in the affected area (wrinkles in older people) or in immunosuppression.

  • Moist chamber due to saliva (irritant contact dermatitis)
  • Humid chamber due to closed folds
  • Bacteria (impetigo)
  • Herpes
  • Yeasts

On one or both commissures there is a rhagade and surrounding inflammation, which may also affect the follicle-bearing skin.

  • Typical clinical picture
  • Pathogen detection

Commissures of the lips, often on both sides, can also affect the surrounding skin.

  • Drainage of wrinkles, anecdotally with hyaluronic acid injection or botulinum toxin
  • Disinfect regularly


  • Antibiotics or fungicidal agents or acyclovir