Ascher syndrome

Last Updated: 2020-08-13

Author(s): Navarini

Double lip, blepharochalasis, goiter (10-50%).

Pediatric dysmorphia syndrome, very rare.

Recurrent swelling of the lips and upper eyelids. A so-called double lip is formed by a special transverse fold (upper lip > lower lip). Blepharochalasis due to prolapse of the subcutaneous fatty tissue of the orbit, as well as glandular parts.

Clinical diagnosis.

Eyelids, lips.

Dermatosurgical / plastic surgery.

Sanchez MR, Lee M, Moy JA et al. Ascher syndrome: a mimicker of acquired angioedema. J Am Acad Dermatol 1993;29:650–651.
U. Beinhoff; H. Piza-Katzer (1998). "Double lip in a patient with Ascher's syndrome". European Journal of Plastic Surgery. 21 (7): 370–373. doi:10.1007/s002380050120.
Atzeni M, et al. Surgical correction and MR imaging of double lip in Ascher syndrome: record of a case and a review of the literature. Eur Rev Med Pharmacol Sci 2009;13:309-311.Gorlin RJ, Pindborg JJ, Cohen MM. Syndromes of the head and neck, 4th ed.New York:McGraw-Hill, 1976: 500-501.