Bowel bypass syndrome
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: EB2Y
Dicken and Seehofer 1979.
BADAS
A dermatosis with systemic symptoms occurring in obese patients after ileo-jejunal bypass surgery. BADAS is one of the classic neutrophilic dermatoses.
Approximately 20% of all patients who have ileojejunal bypass surgery.
After an artificial short bowel is created, large parts of the small bowel are bypassed.
- Erythematous, coarse papules and pustules localised to the trunk as well as the upper and lower extremities
- Flu-like symptoms, joint symptoms (due to circulating immune complexes and cryoglobulins) cryoglobulinemia, tendinitis
- The disease may be associated with xerosis cutis, erythema nodosum and acrodermatitis enteropathica-like skin lesions
- History (Ileojejunal bypass surgery?)
- Clinical
- Histopathological findings
Suspiciously many neutrophilic granulocytes, papillary oedema, sometimes suggested subepidermal vesicle formation, pustules, necrotising vasculitis.
Spontaneous healing as well as long-term, intermittent courses have been described.
- Re-operation if possible
- Doxycycline p.o. 200 mg 1x tgl. for approx. 3 weeks
- Metronidazole p.o. up to 1.5 g/day
- Low-dose oral glucocorticoids
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- Dicken CH. Bowel-associated dermatosis-arthritis syndrome: bowel bypass syndrome without bowel bypass. Mayo Clin Proc 1984;59:43-6.
- Ely PH. The bowel bypass syndrome: a response to bacterial peptidoglycans. J Am Acad Dermatol 1980;2:473-87.
- Geary RJ, Long LL , Mutasim DF. Bowel bypass syndrome without bowel bypass. Cutis 1999;63:17-20.
- Simon SI, Sikka JV , Lynfield YL. Bowel bypass syndrome. Cutis 1981;28:545-7, 50, 79.
- Tu J, Chan JJ , Yu LL. Bowel bypass syndrome/bowel-associated dermatosis arthritis syndrome post laparoscopic gastric bypass surgery. Australas J Dermatol 2011;52:e5-7.
- Varma JR, Pye J , Sinha A. Dermal complication of the bowel bypass syndrome: a case report. J Fam Pract 1993;36:564-6.
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