Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
Subtype of condylomata plana. Carcinoma in situ caused by mostly HPV 16 or 18 (rarely also HPV 31-35, 39, 42, 48, 51-54).
Young patients mostly between 20-30 years old.
Pigmented, verrucous macules and papules. They appear a little lighter in the mucous membrane area.
- Clinical image
- PCR with HPV typing
Genitoanal and on the mucous membranes.
Hyperplastic epidermis, mitoses, dyskeratotic keratinocytes.
- Transition to invasive squamous cell carcinoma is estimated at approximately 1%-2.6%
- Patients are highly infectious, partners should be examined regularly
- Frequent recurrences
- Wade TR. Bowenoid Papulosis of the Genitalia. Arch Dermatol 1979;115:306.
- Takayama A, Ishiguro N, Kawashima M. Coexistence of Bowenoid papulosis and Bowen's disease in a patient with systemic lupus erythematosus. J Dermatol 2012;39:646-9.
- Papadopoulos AJ, Schwartz RA, Lefkowitz A, Tinkle LL, Janniger CK, Lambert WC. Extragenital bowenoid papulosis associated with atypical human papillomavirus genotypes. J Cutan Med Surg 2002;6:117-21.
- Iwai Y, Someya K, Moriya K, Kobayakawa H, Ohyama T, Horii A. [A case of bowenoid papulosis of the penis]. Hinyokika Kiyo 1989;35:517-21.
- Deen K, Burdon-Jones D. Imiquimod in the treatment of penile intraepithelial neoplasia: An update. Australas J Dermatol 2016.
- Majores M, Bierhoff E. [Actinic keratosis, Bowen's disease, keratoacanthoma and squamous cell carcinoma of the skin]. Pathologe 2015;36:16-29.