Condylomata plana

Last Updated: 2019-08-27

Author(s): Anzengruber F., Navarini A.

ICD11: -

HPV 16 and 18-associated precursors of intraepithelial neoplasias in the genitoanal region from vulva to cervix. Flat condylomata acuminata.a.

Skin-coloured, sharply defined, relatively flat (only discreetly raised) papules and plaques with a disruptive surface.

  • Clinic
  • Acetic acid test 5%

Mostly the cervix uteri and the prepuce.

Partner should be examined by a doctor in any case!

Inform patients about the ping-pong phenomenon, which stands for reinfection by the untreated partner. Therefore, both partners should be treated simultaneously.


Topical therapy (mostly off label use!)


Aperture: 2x to 15 seconds.

Note: effective, cheap, short-term unpleasant for patients.




Aldara® 3x a week for 12 weeks.


Individ. 5x/ week over several weeks, maximum 16 weeks.

The wart surface must be removed beforehand.

Side effects: redness, itching, burning, erosion of the skin. Inform Pat. about this before starting therapy!


Condyline® Lin: Apply 2x daily for 3 consecutive days. Repeat if necessary.


Application: Apply 2x daily for 3 consecutive days, protect surrounding skin. Repeat if necessary.

AI: < 12 years, open wounds, women of childbearing age, contraception recommended up to 30 days after therapy, pregnancy, lactation.


Sinecatechins (Veregen® - Ointment) Green Tea Extract

Application: 3x daily for up to 16 weeks.


Trichloroacetic acid 85% (Magistral formulation)

Application: 1x/ week with cotton swabs. Therapy belongs in the hands of a doctor. Also allowed during pregnancy, in case of overdose neutralization with sodium bicarbonatesg.


Removal with CO² laser/electrocution/curette/excision:

CAVE infectivity! Especially when laser cutting and electro chewing. Always wear a face mask or goggles and mouthguard! Smoke extraction is essential.


Other described therapies:

Interferon- β Gel application should be carried out for a maximum of 4 weeks.

In Switzerland only available from pharmacies abroad.

Germany: Fiblaferon® 0.1 million IU/g, 5x daily.

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