Last Updated: 2019-08-27
HPV 16 and 18-associated precursors of intraepithelial neoplasias in the genitoanal region from vulva to cervix. Flat condylomata acuminata.a.
Skin-coloured, sharply defined, relatively flat (only discreetly raised) papules and plaques with a disruptive surface.
- Acetic acid test 5%
Mostly the cervix uteri and the prepuce.
Partner should be examined by a doctor in any case!
Inform patients about the ping-pong phenomenon, which stands for reinfection by the untreated partner. Therefore, both partners should be treated simultaneously.
Topical therapy (mostly off label use!)
Aperture: 2x to 15 seconds.
Note: effective, cheap, short-term unpleasant for patients.
Aldara® 3x a week for 12 weeks.
Individ. 5x/ week over several weeks, maximum 16 weeks.
The wart surface must be removed beforehand.
Side effects: redness, itching, burning, erosion of the skin. Inform Pat. about this before starting therapy!
Condyline® Lin: Apply 2x daily for 3 consecutive days. Repeat if necessary.
Application: Apply 2x daily for 3 consecutive days, protect surrounding skin. Repeat if necessary.
AI: < 12 years, open wounds, women of childbearing age, contraception recommended up to 30 days after therapy, pregnancy, lactation.
Sinecatechins (Veregen® - Ointment) Green Tea Extract
Application: 3x daily for up to 16 weeks.
Trichloroacetic acid 85% (Magistral formulation)
Application: 1x/ week with cotton swabs. Therapy belongs in the hands of a doctor. Also allowed during pregnancy, in case of overdose neutralization with sodium bicarbonatesg.
Removal with CO² laser/electrocution/curette/excision:
CAVE infectivity! Especially when laser cutting and electro chewing. Always wear a face mask or goggles and mouthguard! Smoke extraction is essential.
Other described therapies:
Interferon- β Gel application should be carried out for a maximum of 4 weeks.
In Switzerland only available from pharmacies abroad.
Germany: Fiblaferon® 0.1 million IU/g, 5x daily.
- Herpes Simplex Virus, in SpringerReference. Springer Science + Business Media.
- Drago, F. and A. Rebora, The New Herpesviruses. Arch Dermatol, 1999. 135(1).
- Arvin, A.M., R.J. Whitley, and K.M. Gutierrez, Herpes Simplex Virus Infections, in Infectious Diseases of the Fetus and Newborn Infant. 2006, Elsevier BV. p. 845-865.