Last Updated: 2022-04-01
Author(s): Anzengruber F., Navarini A.
Orf, sheep pox, vaccinoids, livestock pox.
A zoonosis caused by parapoxvirus ovis, a DNA-square virus, with low contagiosity.
- Common disease among sheep farmers
- Self-limiting, but frequent recurrences (an infectious immunity)
- Incubation period: 3-11 days
- Infection occurs via injured skin through direct contact with sheep, lambs and goats. Ecthyma contagiosum occurs mainly in spring.
- Mostly on the extensor sides of the fingers (rarely on the face)
- 1st week: maculopapular stage
- 2nd week: cocard stage
- 3rd week: exudation
- 4th week: formation of a crust
- 5th week: papillomatous transformation, then regression
- Generalisation very rare. Incidental findings often regional lymphadenopathy
Anamnesis, clinic, dermatopathology, virus detection.
Vascular granulation tissue with epidermal ballooned cells and reticular degeneration.
Healing after approx. 5 weeks without scarring.
- Friederichs S, Krebs S, Blum H, et al. Comparative and retrospective molecular analysis of Parapoxvirus (PPV) isolates. Virus Res 2014;181:11-21.
- Bodilsen J, Leth S. [Orf parapoxvirus can infect humans after relevant exposure]. Ugeskr Laeger 2013;175:1121-2.
- Zhang K, Liu Y, Kong H, Shang Y, Liu X. Human infection with ORF virus from goats in China, 2012. Vector Borne Zoonotic Dis 2014;14:365-7.
- de Vicq de Cumptich M, Snoeck R, Sass U, del Marmol V, Binet H. [Orf nodules and immunosuppression: a case report and review of therapeutics]. Rev Med Brux 2015;36:439-43.
- Frandsen J, Enslow M, Bowen AR. Orf parapoxvirus infection from a cat scratch. Dermatol Online J 2011;17:9.
- Turan E, Yesilova Y, Ucmak D. A case of orf (ecthyma contagiosum) with multiple lesions. J Pak Med Assoc 2013;63:786-7.
- Friebel TR, van der Werff JF. The orf virus: a case report. J Hand Surg Eur Vol 2015;40:648-9.