Foreign body granulomas

Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: EH93.3

Pinkus and Bortvinick 1957

Granulomatous reaction triggered by foreign bodies.

They are the most common granulomatous diseases.

Trauma: After foreign bodies have penetrated the skin (milking granuloma, barber's granuloma, pilonidal sinus, sea urchin sting)

In the course of medical treatments (paraffin, sutures, silicone)

Body's own products: Gout (urate crystals), necrotic fatty tissue (lipophagic granuloma).

There is the expression of a granulomatous reaction, in the sense of a disorderly accumulation of macrophages with foreign body giant cells.

Skin-coloured, derb-palpable, well-defined nodules and plaques.

Different dermatopathological patterns are possible (sarcoid, necrobiotic granuloma, zirconium granuloma). The foreign bodies are detectable by polarisation optics.

Friedrich RE et al. Paraffinoma of lips and oral mucosa: Case report and brief review of the literature. GMS Interdiscip Plast Reconstr Surg DGPW. 2014 May 15;3.