Foreign body granulomas

Last Updated: 2019-08-27

Author(s): Anzengruber F., Navarini A.

ICD11: -

Pinkus und Bortvinick 1957

Granulomatous reaction triggered by foreign bodies.

They are the most common granulomatous diseases.

Trauma: After foreign bodies have penetrated the skin (milker granuloma, hairdresser granuloma, pilonidalsinus, sea urchin spines)

In the context of medical treatments (paraffin, sutures, silicone)

Body's own products: Gout (urate crystals), necrotic fatty tissue (lipophagous granuloma).

This leads to a granulomatous reaction, in the sense of a disordered accumulation of macrophages with giant foreign body cells.

Skin-coloured, coarse-palpable, well demarcable knots and plaques.

Different dermatopathological patterns are possible (sarcoid, necrobiotic granulomas, zirconium granuloma). The foreign objects can be detected by polarization optics.

Friedrich RE et al. Paraffinoma of lips and oral mucosa: Case report and brief review of the literature. GMS Interdiscip Plast Reconstr Surg DGPW. 2014 May 15;3.