Granuloma inguinale
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: 1A91
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: 1A91
McLeod 1882.
Donovanosis, granuloma venereum.
Sexual disease caused by the intracellular Calymmatobacterium granulomatis (Donovania granulomatis, Klebsiella granulomatis).
The causative agent is Klebsiella granulomatis, formerly called Calymmatobacterium granulomatosis or Donovania granulomatosis.
Pathogen intracellular in macrophages. In Giemsa staining or silvering, bipolar coccoid intracytoplasmic inclusion bodies (Donovan bodies) can be visualised from clusters of pathogens.
Untreated, peripheral extension occurs in 10% of cases and can assume monstrous proportions. Obstruction of the lymphatic vessels can lead to elephantiasis of the penis, scrotum and labia
Partner co-treatment!
Surgical removal of the exophytic skin lesions.
Topical therapy
Systemic therapy
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