Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: 1F05.1

Zahorsky 1924.

Pharyngitis vesicularis.

Most throat infections occur in summer and autumn, especially in young children and adolescents.

  • Incubation period: 2-9 days
  • Herpangina is caused by type A coxsackie viruses (2, 3, 4, 5, 6, 8, 10)

High, often biphasic fever (up to 40°C), convulsions, nausea and vomiting, diarrhoea and myalgias. In the course of the disease, vesicles appear in the pharyngeal region and the palatum molle. After about 4 days, the vesicles erupt with the formation of ulcers and subsequent healing within 14 days

  • Clinic
  • Virus isolation is possible (CSF, blood, stool, throat lavage water)

  1. Chang LY, King CC, Hsu KH, et al. Risk Factors of Enterovirus 71 Infection and Associated Hand, Foot, and Mouth Disease/Herpangina in Children During an Epidemic in Taiwan. PEDIATRICS 2002;109:e88-e.
  2. Nakayama T, Urano T, Osano M, et al. Outbreak of herpangina associated with coxsackievirus B3 infection. The Pediatric Infectious Disease Journal 1989;8:495-8.