Herpes simplex

Last Updated: 2022-03-11

Author(s): Anzengruber F., Navarini A.

ICD11: 1F00.Z

Cold sore, cold sore, glacier sore, herpes simplex recidivans, herpes simplex recidivans in loco.

Frequent reactivation with reduced defence with herpes simplex virus (HSV). Recurrences at the same site are referred to as herpes simplex recidivans in loco.

  • Incubation period: 2-5 days
  • Weakening of the immune system (febrile infections, psychological and physical stressors, menstruation), UV exposure

Before the appearance of the first skin changes, feeling of tension. Vesicles on an erythematous base, possibly . Lymphadenopathy, in the course bursting and crusting, with subsequent healing (approx. after 7-14 days), usually occurring periorally, but also possible at other localisations.

  • Clinic
  • In unclear cases:
    • viral PCR
    • microtrack
  • Exclude meningism

  • Eczema herpeticatum
  • Keratoconjunctivitis herpetica
  • Erythema exsudativum multiforme
  • In immunocompromised patients, ulcers and haemorrhages may occur
  • Development of lymphoedema possible after longstanding recurrences (elephantiasis nostras)

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