Hydroa vacciniformia

Last Updated: 2019-08-27

Author(s): Anzengruber F., Navarini A.

ICD11: -

Bazin 1862

  • Hidroa vacciniform
  • Hidroa vacciniformis
  • Hidroa vacciniformia

Rare photodermatosis.

Mostly occurring in early childhood.

Frequency peak: spring.


Possibly associated with the Ebstein-Bar virus.

Erythema, papules, urticaria and blisters. In contrast to the polymorphic light reaction, scarring also occurs after blister formation. Central necrosis can also occur.


Clinical picture


Direct immunofluorescence

Photoprovocation (UVA)

Porphyrins in stool and serum (e.g. porphyria)

Areas exposed to light.

Intra- and subepidermal acantholysis. Possibly necroses.

UV protection.

  1. Nitiyarom R, Wongpraparut C. Hydroa vacciniforme and solar urticaria. Dermatol Clin. 2014 Jul;32(3):345-53
  2. Di Lernia V, Mansouri Y. Epstein-Barr virus and skin manifestations in childhood. Int J Dermatol. 2013 Oct;52(10):1177-84.