Kaposi's sarcoma
Last Updated: 2022-07-22
Author(s): Anzengruber F., Navarini A.
ICD11: 2B57.Z
Last Updated: 2022-07-22
Author(s): Anzengruber F., Navarini A.
ICD11: 2B57.Z
Moritz Kaposi, 1872
Human herpes virus 8, HHV-8, sarcoma idiopathicum haemorrhagicum multiplex, Kaposi's disease, Kaposi's angiomatosis, Kaposi's idiopathic multiple pigment sarcoma, teleangiectatic pseudosarcoma, Kaposi's syndrome, angioreticulomatosis, Kaposi's sarcoma, Kaposi's sarcoma.
Multifocally localised angioproliferative neoplasia of different genesis occurring in all age groups with primary cutaneous occurrence and possible metastasis with a correspondingly poor prognosis.
Kaposi's sarcoma can be classified by clinic as follows:
Further classification can be according to Mitsuyasu and Groopman, with staging from Sradium I to IV.
For HIV, ACTG staging should also be used.
Endemic Kaposi's sarcoma can in turn be divided into further subgroups depending on the clinic:
Generally: Enoral, legs, other localisations.
Classical Kaposi's sarcoma particularly affects the feet, lower and upper legs and shows a proximal spread.
In 5-20% there is visceral involvement.HIV-associated Kaposi's sarcoma: tip of the nose, ear, glans penis and trunk area along the skin cleft lines. Extracutaneous manifestation is also frequently seen. 30% of patients have mucosal involvement.
In the course, metastases to the internal organs and lymph nodes may occur.
With regard to HIV-associated Kaposi's sarcoma, attention should be paid to protected sexual intercourse.
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