Keratose palmoplantaris diffusa circumscripta
Last Updated: 2019-08-26
ICD11: -
Last Updated: 2019-08-26
Author(s): Anzengruber F., Navarini A.
ICD11: -
Trost 1880
Unna 1883
Körner 1901
Most common hereditary palmoplantar keratosis.
1:100.000
Autosomal dominant inheritance.
Mutation in the genes keratin 1 and 9.
Laterally blurred, erythematous, thick hyperkeratotic plaques covering the Palmae and Plantae.
There may also be isolated lateral blisters.
Nail changes are described.
Anamnesis.
Clinic.
Biopsy.
Genetic analysis.
Hyperkeratosis, acanthosis.
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