Keratosis palmoplantaris diffusa circumscripta
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: -
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: -
Trost 1880
Unna 1883
Körner 1901
Frequent hereditary palmoplantar keratosis.
1:100,000
Autosomal dominant inheritance.
Mutation in the keratin 1 and 9 genes.
Laterally indistinct, erythematous, thick hyperkeratotic plaques covering the palmae and plantae.
Sporadic blisters may also occur laterally.
Nail changes have been described.
Anamnesis.
Clinic.
Biopsy.
Genetic analysis.
Hyperkeratosis, acanthosis.
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