Keratosis palmoplantaris transgrediens et progrediens with mutation in SLURP1
Last Updated: 2019-08-26
ICD11: -
Last Updated: 2019-08-26
Author(s): Anzengruber F., Navarini A.
ICD11: -
Stulli 1826
Mal de Meleda
Palmoplantare hyperkeratosis caused by a mutation in the SLURP1 gene.
Autosomal - recessive mutation in the gene SLURP1.
Anamnesis
Clinic
Genetic investigation
Palmoplantar, also on the back of hands and feet.
Mycosis superinfections are frequently described.
Keratolysis.
Lipid replenishing topical therapy.
If necessary even prophylactic application of a topical antimycotic once a week.
Acitretin.