Syphilis (Neurosyphilis)
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: 1A62.0Z
Neurological manifestation of syphilis.
- Tabes doralis: demyelination of the hindbrain with disturbance of the sense of movement as well as the sense of vibration
- Paralysis progressiva: cephalgia, dementia, depression, personality changes
Neurological consultation for further clarification.
Neurosyphilis
- Penicillin
- Benzylpenicillin sodium i.v. 2-4 million IU 4-6x daily for up to 3 weeks
- Rockwell DH. The Tuskegee Study of Untreated Syphilis. Arch Intern Med 1964;114:792.
- Posp, iacute, scaron, il L, Kratochvil F. Vor- und Nachteile des Peroxidase-Tests mit <i>Treponema pallidu</i><i>m</i> in der Serodiagnostik von Syphilis im Vergleich mit dem FTA-ABS-Test. Dermatology 1974;149:78-83.
- Crissey JT, Denenholz DA. Clinical picture of infectious syphilis. Clinics in Dermatology 1984;2:39-61.
- Prange HW. Diagnostische Maßnahmen und Kriterien der Neurosyphilis. DMW - Deutsche Medizinische Wochenschrift 1986;111:625-7.
- Marra C. Syphilis and Human Immunodeficiency Virus Infection. Seminars in Neurology 1992;12:43-50.
- van Voorst Vader PC. SYPHILIS MANAGEMENT AND TREATMENT. Dermatologic Clinics 1998;16:699-711.
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