Tinea corporis profunda

Last Updated: 2019-08-27

Author(s): Anzengruber, Navarini

Trichophytia corporis profunda. 

Deep, granulomatous reaction triggered by dermatophyte infection.

  • Erythematous, partly abscessing plaques and nodi. Follicularly bound pustules are not uncommon.
  • Clinic.
  • Detection of pathogens (extraction of dandruff: then native preparation and culture; biopsy)

  • Wood light (greenish fluorescence).

Back of the hand, wrists, forearms, neck, beard area.

  • If zoophilic dermatophytes are detected, all animals with which contact has existed should be examined
  • Examination of other persons in the household.
  • The therapy should be carried out with both topical and systemic antifungals!


Topical Therapy

  • Clotrimazole cream (Canesten® cream)
  • Terbinafin cream (Terbinafin® cream 1%)
  • Ketoconazole cream (Nizoral® cream 2%)
  • Amorolfine cream (Loceryl® 0.25% cream)
  • Griseofulvin cream: not available in Switzerland
  • Bifonazole cream: not available in Switzerland
  • Econazole cream (Pevaryl® cream 1%)

  • Ciclopirox Cream (Ciclocutan® Cream or similar)
  • Ketoconazole-containing shampoo (Ketozol® shampoo, Keto-med® shampoo, Lur® shampoo, Nizoral® shampoo): leave on for 5-10 minutes. 

  • Shampoo containing Ciclopirox (Sebiprox®-Shampoo): leave on for 5-10 minutes. 

  • Pregnancy: Only nystatin is allowed.


Systemic Therapy

  • Terbinafin (Lamisil®, Myconormin®) p.o. 250 mg 1x per day 1-2 weeks.

  • Alternative: Fluconazole (e.g.: Diflucan®) p.o. 50 mg 1x per day for 14 days

  • Alternative: itraconazole (e.g. Sporanox®) p.o. 200 mg 1x per day for 7 days

  • Alternative: Griseofulvin p.o. 500 mg 2x per day (not available in Switzerland)

  • Children: Although only griseofulvin is approved for children, we recommend the use of itraconazole for the data situation. 

  1. Goldstein, A. (2016). Dermatophyte (tinea) infections. Uptodate.com. Retrieved 30 May 2016, from http://www.uptodate.com/contents/dermatophyte-tinea-infections?source=search_result&search=tinea+corporis&selectedTitle=1~51