Tuberculosis ulcerosa mucosae et cutis

Last Updated: 2019-08-26

Author(s): Anzengruber F., Navarini A.

ICD11: -

Tuberculosis orificialis.

Tuberculous infestation of the mucous membranes occurring with pronounced immunosuppression.

Men from the middle age are preferably afflicted.

The disease occurs when the immunity situation is unfavourable.

  • Localisations
  • Enoral, perioral.
  • The term infectious tuberculosis refers to the infection of the sites through which secretions rich in tubercle bacteria are excreted (anus, rectum, kidney, lung).

  • Enoral (from larynx to lips) and perioral dolent, ulcerating papules and pustules.

  • CAVE: The contact density is particularly high due to the high number of tubercle bacteria in the skin lesions. 

  • Travel medical history
  • Clinic.

  • The tuberculin test is often false negative (due to the usually poor immune situation).

  • Quantiferon test. 
  • Biopsy.
  • To exclude system involvement:

  • Thorax X-ray or CT thorax.
  • Sonography of the abdomen and kidneys.

  • In the morning (fasting up to 4h) on 3 consecutive days sputum must be collected.

  • In the morning on 3 consecutive days urine must be given (fluid restriction the evening before!).

  • Bronchoalveolar lavage (BAL).

Non-specific, cellular proliferating, partly necrotizing inflammation, tuberculoid granulomas.

In most cases, disseminated organ infestation occurs.

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