Tuberculosis ulcerosa mucosae et cutis

Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: -

Tuberculosis orificialis.

In cases of pronounced immunosuppression, tuberculous infestation of the mucous membranes.

Men from middle age onwards are preferentially affected.

The disease occurs in the case of an unfavourable immune situation.

  • Localisations: Enoral, perioral
  • The term staphylococcal tuberculosis refers to the infection of the localisations through which secretions rich in tubercle bacilli are excreted (anus, rectum, kidney, lungs)
  • Enoral (from the larynx to the lips) and perioral stool-like ulcerative papules and pustules
  • CAVE: Contagiousness is particularly high due to the high number of tubercle bacilli in the skin lesions!

  • Travel history
  • Clinical
  • Tuberculin test is often false negative (due to usually poor immune status)
  • Quantiferone test
  • Biopsy
  • To exclude systemic involvement:
    • Thoracic X-ray or CT- thorax
    • Sonography of the abdomen and kidneys
    • In the morning (fasting up to 4h) on 3 consecutive days, sputum must be collected
    • Pass urine in the morning on 3 consecutive days (fluid restriction the evening before!)
  • Bronchoalveolar lavage (BAL)

  • Enoral
  • Perioral

Nonspecific, cellular proliferating, partly necrotising inflammation, tuberculoid granulomas.

Most often, disseminated organ infestation occurs.

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