Vitiligo
Last Updated: 2021-10-15
ICD11: ED63.0
Last Updated: 2021-10-15
Author(s): Anzengruber F., Navarini A.
ICD11: ED63.0
White spot disease
Acquired disease in which CD8+ T-lymphocytes attack melanocytes leading to depigmentation of the skin.
As yet not explained in detail.
Sharply demarcated, often symmetrical, partly confluent, pigment-free, whitish macules. In some cases an erythematous border is visible (dermatitis circinata Miescher). Hair arising from follicles in the affected areas typically turn whitish (poliosis circumscripta).
Mostly on the face, hands, axillae / nipples / periumbilical or genitoanal region. First depigmentation is often seen periorally. Watch out for traces of tooth paste around the mouth in children - this imitates perioral vitiligo in the Wood light examination. Wiping with a wet tissue helps!
Decrease or absence of melanin and melanocytes (melanin and melan-A staining).
Frequent progression in relapses.
Topical therapy
Camouflage make up
Bleaching agent
Laser
Phototherapy
Systemic therapy
Surgical
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