Colchicine

Colchicine
Blood count, liver values, kidney values, lipids, SS test, possibly SD values
p.o.
3x0,5 to 3x1,0 mg/d
1 to 2 weeks
Many interactions: Clarify (interaction check): e.g. fluconazole, statins, erythromycin, cyclosporine, various antihypertensives
Pregnancy / lactation; liver dysfunction, alcohol abuse, relative contraindication Active hepatitis
Stomatitis, nausea, upper abdominal complaints, diarrhoea, vomiting, transaminase increase -> interruption. Contraception, obtain signature.
2 weeks to years, low maintenance doses possible e.g. 0.5 mg - 1 mg/d