Actinic prurigo
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: EJ30.Y
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: EJ30.Y
Lopez-Gonzáles 1961
Hereditary polymorphous light dermatosis
Familial actinic prurigo
Women>men.
Mostly occurring in childhood.
Familial variants are seen in the indigenous population of the Americas.
The main cause is UV-B and also UV-A radiation. The further pathomechanism is unknown. Some authors postulate a UV-induced hypersensitivity reaction of the delayed type
Mostly there is an association with an atopic diathesis.
Initially in areas exposed to light, urticarial skin lesions develop into lichenified plaques and prurigo nodules. Cheilitis is often visible as well.
Anamnesis
Clinic
Photoprovocation test
If necessary, biopsy
Acanthosis, sponiogsis, dermal infiltration of lymphocytes and histiocytes (sometimes also eosinophils), especially perivascularly.
Pseudopterygium
UV protection (incl. sunglasses)- incl. UVA!
Light hardening
Spontaneous remission at puberty.
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