Actinic Prurigo
Last Updated: 2019-08-27
ICD11: -
Last Updated: 2019-08-27
Author(s): Anzengruber F., Navarini A.
ICD11: -
Lopez-Gonzáles 1961
Hereditary polymorphic light dermatosis
Familiar actinic prurigo
Women>Men.
Mostly occurring in childhood.
Family variants can be seen in the indigenous population of America.
This is caused by UV-B and UV-A radiation. The further pathomechanism is unknown. Some authors postulate a UV-induced hypersensitivity reaction of the delayed type.
Usually there is an association to an atopic diathesis.
Initially urticarial skin lesions in areas exposed to light, which develop into lichenified plaques and prurigo nodules in the course of time. Cheilitis is often also visible.
Medical history
Clinic
Photo Provocation Test (LINK)
Biopsy, if necessary
Acanthosis, spongiosis, dermal infiltration of lymphocytes and histiocytes (partly also eosinophils), especially perivascular.
Pseudopterygium
UV protection (incl. sunglasses)- incl. UVA!
Light hardening (LINK)
Spontaneous remission during puberty.
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