Last Updated: 2019-08-27

Author(s): Anzengruber F., Navarini A.

ICD11: -

  • Odriozola 1895.
  • Barton 1909.

  • Verruga peruana.
  • Carrion’s disease.
  • Oroya fever.

Infectious disease that leads not only to cutaneous manifestation but also to sepsis.

  • Occurs only in the high mountain valleys (600-3000m) of Peru, Ecuador and southwest Colombia.
  • It is expected that about 5% of the population of the endemic area are asymptomatic carriers.

  • Pathogen: Bartonella bacilliformis.
  • Transmission: Sand flies of Lutzomyia spp., especially Lutzomia verrucarum.
  • The transfer takes place during the sucking cycle and after blood transfusions.
  • Incubation period: weeks - months.

  • Bartonella bacilliformis causes both dermal nodules (Verruga peruana) and sepsis (Oroya fever).
  • Cutaneous manifestation includes stemmed, cruciform, grouped and eroded papules and nodi. The face, extremities and mucous membranes are particularly affected. Petechial exanthema.
  • Sepsis, reduced general condition, fever, anemia, hepatosplenomegaly, lymphadenopathy
  • A second infection with salmonella can occur.

  • Travel history.
  • Clinic.
  • Detection of pathogens by blood culture or biopsy.

  • Similar to bacillary angiomatosis.
  • The detection of bacteria is successful by means of warthin-starry staining.

  • Letality: 10-90%.
  • The survivors heal spontaneously, often after years of existence.

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