Last Updated: 2020-08-17
Infection with Clostridium botulinum that is legally required to report.
- Smoked meats, canned foods, honey.
- C. botulinum secretes toxins, which inhibits the presynaptic release of acetylcholine.
- Muscle paralysis.
- Dry mouth.
- Impaired vision.
- Medical history (what was eaten).
- Clinical features.
- Obligation to report.
- Hospitalization (CAVE: renal insufficiency).
- Treatment with a botulism antitoxin (A-G) and/or B. immunoglobulin.
A lack of botulinum toxin has become unthinkable in aesthetic medicine today. Wrinkles, torticollis and hyperhidrosis are now treated by the above described mode of action.
- Rosow LK , Strober JB. Infant botulism: review and clinical update. Pediatr Neurol 2015;52:487-92.
- Chalk CH, Benstead TJ , Keezer M. Medical treatment for botulism. Cochrane Database Syst Rev 2014;2:CD008123.
- Brown N , Desai S. Infantile botulism: a case report and review. J Emerg Med 2013;45:842-5.
- Moreira GM, Cunha CE, Salvarani FM, Goncalves LA, Pires PS, Conceicao FR et al. Production of recombinant botulism antigens: a review of expression systems. Anaerobe 2014;28:130-6.
- Webb RP , Smith LA. What next for botulism vaccine development? Expert Rev Vaccines 2013;12:481-92.