Last Updated: 2019-08-26
Patients with epidemic spotted fever may have a late recurrence if antibiotic therapy is discontinued prematurely
- Pathogen: Rickettsia prowazekii.
- Lice infestation.
- BB (leukopenia, eosinophilia), liver and kidney values, electrolytes.
- From the 2nd week of disease Weil-Felix reaction (agglutination test).
- Complement fixation reaction from the 3rd week of the disease.
- Indirect immunofluorescence test after the 3rd week of the disease.
- Lifelong immunity only exists after a completely survived illness!
- High lethality
- Bechah, Y., et al., Epidemic typhus. Lancet Infect Dis, 2008. 8(7): p. 417-26.
- McQuiston, J.H., et al., Brill-Zinsser disease in a patient following infection with sylvatic epidemic typhus associated with flying squirrels. Clin Infect Dis, 2010. 51(6): p. 712-5.
- Ormsbee, R., et al., Serologic diagnosis of epidemic typhus fever. Am J Epidemiol, 1977. 105(3): p. 261-71.