Cytomegalovirus

Cytomegalovirus, CMV, human herpesvirus 5, HHV 5.

Viral infectious disease. The human herpes virus 5 acts as the trigger.

• Worldwide, approx. 50-80% of the population is contaminated
• Prevalence regressive

• Transmission by droplet infection, smear infection, transplantation and transfusion
• After the virus has established itself in the mucosa of the oropharynx, viral replication and haematogenous spread via leucocytes
• occurs
• Most of the time, CMV infection is asymptomatic

• May cause rejection after bone marrow or organ transplantation
• Intrauterine infections may lead to microcephaly, cataract, optic atrophy and intracerebral calcifications
• Monucleosis-like clinic

• Viral PCR

• CMV chorioretinitis
• Pneumonia
• Skin ulceration in HIV patients

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