Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: 1D82.Z

Cytomegalovirus, CMV, human herpesvirus 5, HHV 5.

Viral infectious disease. The human herpes virus 5 acts as the trigger.

  • Worldwide, approx. 50-80% of the population is contaminated
  • Prevalence regressive

  • Transmission by droplet infection, smear infection, transplantation and transfusion
  • After the virus has established itself in the mucosa of the oropharynx, viral replication and haematogenous spread via leucocytes
  • occurs
  • Most of the time, CMV infection is asymptomatic

  • May cause rejection after bone marrow or organ transplantation
  • Intrauterine infections may lead to microcephaly, cataract, optic atrophy and intracerebral calcifications
  • Monucleosis-like clinic

  • Viral PCR

  • CMV chorioretinitis
  • Pneumonia
  • Skin ulceration in HIV patients

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