Last Updated: 2022-03-11
Urticaria solaris, solar urticaria, photoallergic urticaria, solar urticaria
A form of urticaria that can be triggered by UV radiation (from infrared to UVC).
UV radiation (from short-wave IR to long-wave UVC rays) is the trigger. Almost all patients react to visible light. A precursor of the allergen (chromophore) absorbs incident UV radiation and becomes the photoallergen. Specific IgE causes histamine release and the development of urticaria.
Urticaria in the area of UV-exposed sites. In rare cases, Quincke's oedema and an anaphylactic reaction may occur.
Photoprovocation testing (UVA, -B, -C, IR, visible light) with determination of minimum urticaria dose (MUD)
Anaphylactic reactions have been described in case of whole body exposure.
Light hardening: The habituation effect usually lasts only a few days.
- PUVA therapy
Prednisolone approx. 0.5-1 mg / kg bw 1x daily, rapidly tapering off.
Antihistamines e.g. Xyzal 5 mg 1x tgl.
Ciclosporin 3-5mg /kg bw short-term.