Lupus erythematosus

Last Updated: 2021-12-20

Author(s): Anzengruber, Navarini

  • Cazenave and Schedel, 1833
  • Kaposi, 1872
  • Leloir, 1890

Lupus erythematosus, LE, erythematodes, butterfly lichen, Leloir's disease.

  • Autoimmune disease of the skin and multiple internal organs.
  • Peak in frequency: 20th - 40th year
  • F:M = 3:1
  • The prevalence of cutaneous LE is 3x higher than that of SLE
  • Systemic lupus erythematodes (SLE)
  • Cutaneous lupus erythematosus (CLE)
    • Acutaneous cutaneous lupus erythematosus (ACLE)
      • Localised ACLE
      • Generalised ACLE
    • Subacute cutaneous lupus erythematosus (SCLE)
      • Annular SCLE
      • Papulosquamous SCLE
    • Intermittent cutaneous LE
      • Lupus erythematosus tumidus
    • Chronic cutaneous lupus erythematosus (CCLE)
      • Discoid lupus erythematosus
      • Localised DLE
      • Generalised DLE
    • Mucosal DLE
      • Oral DLE
      • Conjunctival DLE
    • Lupus erythematosus verrucosus (hypertrophicus)
    • Lupus erythematosus profundus (lupus erythematosus panniculitis)
  • Special forms
    • Rowell's syndrome
    • Chilblain lupus
    • Medication-induced lupus erythematosus