Progressive macular hypomelanosis

Last Updated: 2021-08-20

Author(s): Navarini

Guillet 1988

Dyscromie créole

Between 10 and 50 years of age. Persons with a darker complexion are more frequently affected, especially with mixed (referring to the Fitzpatrick skin type) parents. 

Either genetic or due to propionibacterium acnes, check for reddish fluorescence at the edge of patches with Wood light. 

The trunc and sometimes the legs is affected by chronic, disseminated, roundish confluent hypomelanotic patches. No scaling. Median regions most often affected and highest density there. 

Clinical.

Trunc, legs.

UVB / PUVA Phototherapy 

Fistarol et al. Pigmentstörungen. 2010, JDDG 8: 187-203

Böhm et al. Differenzialdiagnostik der Hypomelanosen. 2015, Hautarzt 66: 945-958

Petersen et al. Propionibacterium Acnes Phylogenetic Type III is Associated with Progressive Macular Hypomelanosis. 2017, Eur J Microbiol Immunol (Bp) 7:37-45.