Progressive macular hypomelanosis

Last Updated: 2021-08-20

Author(s): Navarini A.

ICD11: -

Entity described by

Guillet 1988

Synonym (s)

Dyscromie créole

Epidemiology

Between 10 and 50 years of age. Persons with a darker complexion are more frequently affected, especially with mixed (referring to the Fitzpatrick skin type) parents.

Etiopathogenesis

Either genetic or due to propionibacterium acnes, check for reddish fluorescence at the edge of patches with Wood light.

Clinical features

The trunc and sometimes the legs is affected by chronic, disseminated, roundish confluent hypomelanotic patches. No scaling. Median regions most often affected and highest density there.

Diagnosis

Clinical.

Localization

Trunc, legs.

Therapy

UVB / PUVA Phototherapy

References

Fistarol et al. Pigmentstörungen. 2010, JDDG 8: 187-203

Böhm et al. Differenzialdiagnostik der Hypomelanosen. 2015, Hautarzt 66: 945-958

Petersen et al. Propionibacterium Acnes Phylogenetic Type III is Associated with Progressive Macular Hypomelanosis. 2017, Eur J Microbiol Immunol (Bp) 7:37-45.