Trichorrhexis nodosa

Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: ED73.Y

Wilks 1852

Hair nodule disease, trichonodosis.

Nodular hair anomaly.

Defects of the cuticle lead to a reduction of intercellular cementum and cortical cells. Due to this weakening of the hair skeleton, (incomplete) shaft fractures may occur.


Possible association:

  • Ectodermal dysplasias
  • Keratosis follicularis
  • Syndromes, such as: Menkes, Bjoernstad and Netherton syndromes and ichthyosis congenita

Dry, dull hair. Knotty, light-coloured frizz is often visible.


Avoiding trauma.

  1. Haskin A, Kwatra SG, Aguh C. Breaking the cycle of hair breakage: pearls for the management of acquired trichorrhexis nodosa. J Dermatolog Treat. 2017 Jun;28(4):322-326
  2. Sisto T, Bussoletti C, D'Amore A, Favoriti N, Fania L, Celleno L. Inability to grow long hair: a presentation of trichorrhexis nodosa. Cutis. 2015 Mar;95(3):E15-6.