Trichorrhexis nodosa

Last Updated: 2019-08-26

Author(s): Anzengruber F., Navarini A.

ICD11: -

Wilks 1852

Hair nodule disease, trichonodosis.

Nodular hair anomaly.

Cuticula defects lead to a reduction in intercellular cement substance and cortical cells. This weakening of the hair skeleton can lead to (incomplete) shaft fractures.


Possible association:

  • Ectodermal dysplasias 
  • Keratosis follicularis 
  • Syndromes, like: Menkes, Bjoernstad and Netherton syndrome and ichthyosis congenita 

Dry, dull hair. Nodular, light distensions are often visible.


Avoiding trauma.

  1. Haskin A, Kwatra SG, Aguh C. Breaking the cycle of hair breakage: pearls for the management of acquired trichorrhexis nodosa. J Dermatolog Treat. 2017 Jun;28(4):322-326
  2. Sisto T, Bussoletti C, D'Amore A, Favoriti N, Fania L, Celleno L. Inability to grow long hair: a presentation of trichorrhexis nodosa. Cutis. 2015 Mar;95(3):E15-6.