Tuberculosis fungosa serpiginosa (consolidation phase)

Last Updated: 2019-08-26

Author(s): Anzengruber, Navarini

  • Therapy schedule:

·         The initial phase should last 8 weeks/2 months. During this time, the majority of bacteria are killed. In the following therapy phase (which lasts for months), an attempt is made to eliminate the remaining bacteria. The antituberculous therapy should be continued for at least 2 months after the absence of skin symptoms.

 

·        The therapy should last individually between 12-24, but at least 6 months!

 

·         Induction phase (2 months):

  • #Rifampicin p.o. 10 mg/kg bw/ d
  • #Isoniazid p.o. 5 mg/kg bw. (with Vit B 6)
  • #Pyrazinamide p.o. 35 mg/kg bw/d combination with allopurinol if necessary!
  • #Ethambutol p.o. 15 mg/kg bw/ d

  • A clear improvement can be seen in the vast majority of cases after 1 month at ½ .

 

·         Consolidation phase:

  • Induction phase (2 months):
  • #Rifampicin p.o. 10 mg/kg bw/ d
  • #Isoniazid p.o. 5 mg/kg bw. (with Vit B 6)
  • #Ethambutol p.o. 15 mg/kg bw/d (may also be omitted if isoniazid resistance has been excluded)
  • HIV patient: Therapy must be done at ≥ for 7 months. Ethambutol should be replaced by #Streptomycin p.o. 15-20 mg/kg bw/d (from > 60 years max 750 mg) in case of additional therapy with NNRTI.

  • Moist, antiseptic compresses e.g.: Lavasept®-Lsg. or Octenisept®-Lsg.

  • Surgical removal if necessary.