Ulcus molle
Last Updated: 2021-10-15
ICD11: 1A90
Last Updated: 2021-10-15
Author(s): Anzengruber F., Navarini A.
ICD11: 1A90
Soft chancre, Chancroid.
Venereal disease caused by Haemophilus ducreyi, which is commonly called soft chancre and occurs mainly in tropical-subtropical areas.
Significant numerical decline in recent years. Endemic in the countries of tropical Africa and South East Asia, on the Indian subcontinent and in South America.
The transmission is caused by a smear infection.
Up to 5 days after infection, soft papules ulcerating in the genital region, portio, perineum or anus. Unilateral lymphadenitis occurs, which can lead to melting and fistula formation after 2-3 weeks.
Unprotected sex?
Men: frenulum, foreskin
Women: vulva, cervix, perianal
In a biopsy from the ulcer base, Giemsa staining can be used to visualize the organism in granulation tissue inside and outside macrophages.
Ulcus molle lymphangitis with development of abscesses. Without therapy, fistulations occur after lymph node cedation. Risk of further infections (other STI) is greatly increased.
Always also treat the partner! (including STI screening)
Systemic therapy
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