Ulcus molle
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: 1A90
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: 1A90
Soft chancre, Chancroid.
Sexual disease caused by Haemophilus ducreyi, which is popularly known as soft chancre and occurs mainly in tropical-subtropical areas.
Significant decline in numbers in recent years. Endemic in the countries of tropical Africa and Southeast Asia, on the Indian subcontinent and in South America.
Transmission occurs through smear infection.
Up to 5 days after infection, ulcerating soft papules occur in the genital region, the portio, the perineum or the anus. Unilateral lymphadenitis occurs, and after 2-3 weeks there may be fusion with fistula formation.
Men: frenulum, prepuce
Women: Vulva, cervix, perianal
In a biopsy from the base of the ulcer, Giemsa staining can be used to visualise the organism in the granulation tissue inside and outside macrophages.
Ulcus molle lymphangitis with formation of abscesses. Without therapy, fistulation follows lymph node abscessation. Risk of further infections (other STI) greatly increased.
Always include therapy for the partner! (incl. STI screening)
Systemic therapy
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