Radiodermatitis acuta

Acute X-ray dermatitis, acute radiation dermatitis, acute radiodermatitis.

Inside 6-12 days, dermatitis triggered by ionising radiation (α-, β-, γ-rays)

• Grade I: Erythema
• Grade II: vesicles and blisters. Loss of hairiness
• Grade III: Ulcers, tissue necrosis

Regular dermatological examinations to rule out neoplasia.

Not during radiation exposure (e.g.: only after completion of radiotherapy).

Grade I & II

• Triclosan skin wash lotion
• Polihexanide solution
• Topical therapy
  • Mometasone fuorate cream / solution / ointment
  • Clobetasol cream 1-2 dgl (for 1-3 days)
  • Tanning agents Lsg. (for hand baths).
  • Iodine-povidone solution/ wound ointment / ointment gauze

Grade III:

• Stage appropriate wound therapy
• Systemic therapy
  • Acetylsalicylic acid p.o. 500 mg 3x tgl.
  • Tramadol 20-40 drops t.gl.
  • Ibuprofen p.o. 400-800 mg tgl. if required.

1. Costa MM, Silva SB, Quinto AL, et al. Phototherapy 660 nm for the prevention of radiodermatitis in breast cancer patients receiving radiation therapy: study protocol for a randomized controlled trial. Trials 2014;15:330.
2. Palatty PL, Azmidah A, Rao S, et al. Topical application of a sandal wood oil and turmeric based cream prevents radiodermatitis in head and neck cancer patients undergoing external beam radiotherapy: a pilot study. Br J Radiol 2014;87:20130490.
3. Katayama Y, Yamawaki S, Yoshimura M, et al. Severe Acute Radiodermatitis in a Keloid Patient with Takayasu's Arteritis. Plast Reconstr Surg Glob Open 2014;2:e270.
4. Cui Z, Xin M, Yin H, Zhang J, Han F. Topical use of olive oil preparation to prevent radiodermatitis: results of a prospective study in nasopharyngeal carcinoma patients. Int J Clin Exp Med 2015;8:11000-6.