Acneiform exanthema

Medication-induced acne without formation of comedones.

Medicines such as:

• EGF receptor drugs (e.g. cetuximuab)
• Lithium
• Phenobarbiturates
• Vitamin B
• Glucocorticoids

Pustules and papules.

Anamnesis (medication)

Clinic

Biopsy

Diff. BB, liver and kidney values (in case of exanthema e.g. of an AGEP)

Taking medication?

Discontinuation of medication if necessary, but this is not always mandatory (EGFR).

Elocom cream 1x daily.

1. Wehler TC, Graf C, Möhler M, Herzog J, Berger MR, Gockel I, Lang H, Theobald M, Galle PR, Schimanski CC. Cetuximab-induced skin exanthema: prophylactic and reactive skin therapy are equally effective. J Cancer Res Clin Oncol. 2013 Oct;139(10):1667-72.
2. Yamada M, Iihara H, Fujii H, Ishihara M, Matsuhashi N, Takahashi T, Yoshida K, Itoh Y. Prophylactic Effect of Oral Minocycline in Combination with Topical Steroid and Skin Care Against Panitumumab-induced Acneiform Rash in Metastatic Colorectal Cancer Patients. Anticancer Res. 2015 Nov;35(11):6175-81.
3. Giuliani J, Marzola M. Skin rash during erlotinib for advanced non-small cell lung cancer: is age a clinical predictor? Arch Dermatol Res. 2013 Sep;305(7):653-8.