Herpes simplex

Fieberbläschen, cold sore, Gletscherbrand, Herpes simplex recidivans, Herpes simplex recidivans in loco.

Häufigste Reaktivierung bei reduzierter Abwehr mit HSV. Bei Rezidiven an der selben Stelle spricht man von einem Herpes simplex recidivans in loco.

Hohe Durchseuchung der Bevölkerung, allerdings stetig abnehmend. Seroprävalenz bei HSV-1 bis 90%, bei HSV-2 10-40%.

• Inkubationszeit: 2-5 Tage
• Schwächung des Immunsystems (fieberhafte Infekte, psychische und physische Stressoren, Menstruation), UV-Exposition

Vor Auftreten der ersten Hautveränderungen, Spannungsgefühl. Bläschen auf erythematösen Grund, gegebenenfalls . Lymphadenopathie, Im Verlauf Aufplatzen und Verkrustung, mit anschliessender Abheilung (ca. nach 7-14 Tagen), meist perioral auftretend, jedoch auch an anderen Lokalisationen möglich.

• Klinik
• ggf. Biopsie
• EM
• Kultur
• PCR
• Microtrack
• Meningismus ausschliessen

• Ekzema herpeticatum
• Keratoconjunctivitis herpetica
• Erythema exsudativum multiforme
• Bei immunsupprimierten Patienten können Ulzera und Hämorrhagien auftreten
• Ausbildung eines Lymphödems nach langjährigen Rezidiven möglich (Elephantiasis nostras)

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