Acute cutaneous lupus erythematosus (ACLE)
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
Initial form of cutaneous lupus erythematosus.
Typical first manifestation at the age of 20-50 years.
- Classic butterfly erythema, may scale somewhat.
- No scars are found after healing of the butterfly rash, but there may be pigmentary ageing (scars are found after discoid lupus lesions).
- see cutaneous lupus erythematosus.
- Note: In ACLE, serological work-up is usually non-specific. SS-A/B and dsDNA antibodies may be positive.
UV-exposed areas, especially face (cheeks, eminence-based one sees recesses of the nasolabial folds, though not always). May also affect trunk and extremities.
see cutaneous lupus erythematosus.
- Walling HW, Sontheimer RD. Cutaneous lupus erythematosus: issues in diagnosis and treatment. Am J Clin Dermatol 2009;10:365-81.
- Okon LG, Werth VP. Cutaneous lupus erythematosus: diagnosis and treatment. Best Pract Res Clin Rheumatol 2013;27:391-404.
- Kuhn, A. (2016). S1-Leitlinie: Kutaner Lupus Erythematodes. Awmf.org. Retrieved 30 May 2016, from http://www.awmf.org/leitlinien/detail/ll/013-060.html