Last Updated: 2019-08-27

Author(s): -

  • Crocq 1896
  • Akroasphyxie
  • Acrocyanosis
  • Acroasphyxia
  • Discoloration of the acra (blue-white) due to reduced blood supply (cyanosis).

  • Cyanotic (oxygen-poor) blood remains in the venous capillary legs and venules. Arterioles are constricted. This leads to a lack of oxygen. Reasons for this include:


  • Idiopathic
  • Genetic disposition
  • Vegetative dysregulation of microcirculation
  • Nerve-related disorders


  • Association: Livedo reticularis.
  • Whitish bluish skin discoloration. Numbness is described.
  • Medical history
  • Clinic
  • Above all, the acra are affected.
  • Frostbite
  • Verrucae vulgaris
  • Pernions
  • Mycotic infections
  • This often leads to a suspension of symptoms in middle age.
  • Education about harmlessness.
  • Protection against the cold
  • Vascular training (alternating baths)
  • Nicotine parental leave.


  • If necessary ASA 100 mg 1x daily


  • Topical nicotinic acid derivatives 2x daily

[1]          Heidrich H. Functional vascular diseases: Raynaud's syndrome, acrocyanosis and erythromelalgia. Vasa. 2010;39; 33-41.

[2]          Kurklinsky AK, Miller VM, Rooke TW. Acrocyanosis: the Flying Dutchman. Vasc Med. 2011;16; 288-301.

[3]          Planchon B, Becker F, Carpentier PH, Lazareth I, Le Devehat C, Levesque H, et al. [Acrocyanosis: changing concepts and nosological limitations]. J Mal Vasc. 2001;26; 5-15.