Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: 1A36.Z

Gastrointestinal disease, which may manifest as cutaneous ulcers, diarrhoea and liver abscesses.

  • Endemic in tropics and subtropics.
  • In Central Europe, however, the prevalence is only approx. 1%.
  • Increasingly found in homosexual men.

  • Trigger: poor hygienic conditions, homosexual contacts.
  • Pathogen: Entamoeba histolytica (mainly in endemic areas) and E. dispar (mainly in homosexuals)

  • Acute diarrhoea
  • Ulcers in perineal/genital area
  • Liver abscess

  • Histories regarding travel, sexual orientation and symptoms
  • Clinical
  • Stool
    • Culture
    • ELISA (pathogen detection)
    • PCR
  • Biopsy
  • When liver abscesses are suspected- ultrasound

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  2. Shirley DA, Moonah S. Fulminant Amebic Colitis after Corticosteroid Therapy: A Systematic Review. PLoS Negl Trop Dis. 2016 Jul 28;10(7):e0004879. doi: 10.1371/journal.pntd.0004879. eCollection 2016 Jul. 
  3. Campos-Rodríguez R, Gutiérrez-Meza M, Jarillo-Luna RA, Drago-Serrano ME, Abarca-Rojano E, Ventura-Juárez J, Cárdenas-Jaramillo LM, Pacheco-Yepez J. A review of the proposed role of neutrophils in rodent amebic liver abscess models. Parasite. 2016;23:6. doi: 10.1051/parasite/2