Buruli ulcer
Last Updated: 2020-08-13
ICD11: 1B21.20
Last Updated: 2020-08-13
Author(s): Anzengruber F., Navarini A.
ICD11: 1B21.20
Buruli ulcer.
Granulomas with giant Langerhans cells, acanthosis, hyperkeratosis.
The occurrence of widespread necroses and the sowing of mycobacteria on the bones is possible. Spontaneous remission with scarring is possible.
Therapy after Lebwohl |
Level of evidence |
Rifampin p.o. 10 mg/kg bw and Streptomycin i.m. 15 mg/kg bw daily for- 412 weeks | B |
Surgical removal alone | B |
Surgical removal and Rifampin p.o. 10 mg/kg bw daily and Ciprofloxacin p.o. 250-500 mg 2x daily for 3-6 months | B |
Rifampicin p.o. 10 mg/ kg bw/d and Clarithromycin p.o. 12-15 mg/kg bw for 2-6 months and surgical measures | B |
Rifampin p.o. 10 mg/kg bw/d and Moxifloxacin p.o. 400 mg 1x daily for 3-6 months. | C |
Ciprofloxacin p.o. 500 mg 2x daily and Clarithromycin p.o. 500 mg 2x daily for 3-6 months and surgical removal. | C |
Rifampicin 10 mg/kg bw 1x daily and Moxifloxacin p.o. 400 mg 2x daily for 3-6 months and surgical removal. | C |
Hyperthermia (40°C) | C |
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