Cowpox

Variola vaccina.

Zoonosis caused by the poxvirus bovis (orthopoxvirus). Rodents (e.g. rats) are the main reservoir of the pathogen, but humans, cats and cattle can be infected.

• Risk groups: Atopics, immunosuppressed patients

Transmission occurs via rodents and cattle, but mainly via cats. Skin lesions serve as a portal of entry.

After the appearance of erythema, papulovesicles and pustules, ulceration occurs (after about 2 weeks). In addition to local swelling, painful lymphadenitis is often seen. Sometimes a reduced AZ, febrile temperatures and ocular involvement are seen.

• clinic
• Electron microscopy (negative contrast)
• Serology
• Detection of pathogens

• In almost 50% of cases, the hands or fingers are affected, otherwise the face and neck

• Topically antiseptic
• Approved systemic drugs do not exist. Cidovir has shown efficacy in studies, but its use is debatable due to potentially lethal side effects

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