Lupus erythematosus, cutaneous type
Last Updated: 2023-10-12
Author(s): Anzengruber F.
ICD11: EB5Z
Last Updated: 2023-10-12
Author(s): Anzengruber F.
ICD11: EB5Z
Special form of lupus erythematosus, which is only localised on the skin. Internal organs are not affected
Possible triggers and trigger factors:
After dermatopathological confirmation of the diagnosis:
Serological parameters of the different subtypes of CLE |
||||
Serology (antibodies) |
ACLE |
SCLE |
DLE |
LET |
ANA |
+++ |
++ |
+ |
(+) |
Anti-ds DNS |
+++ |
0 |
0 |
0 |
Anti-Sm |
++ |
0 |
0 |
0 |
Anti-Ro/SSA |
+-++ |
+++ |
0 |
(+) |
Anti-La/SSB |
(+) |
++(+) |
0 |
(+) |
Source: Kuhn, A. (2016). S1 guideline: Cutaneous Lupus Erythematosus. Awmf.org. Retrieved 30 May 2016, from http://www.awmf.org/leitlinien/detail/ll/013-060.html
Frequency of a positive lupus band test in relation to LE subtype and location |
|||
|
|
Lesional (%) |
Non-lesional (%) |
ACLE |
|
90 |
50-60 |
SCLE |
|
60 |
25 |
DLE
|
Neck |
80-90 |
0 (not exposed to the sun) |
Arms |
80 |
0 (not exposed to the sun) |
|
Trunk |
20 |
0 (not exposed to the sun) |
|
LEP |
|
80 |
not known |
LET |
|
50 |
23 |
Healthy control |
Sun-exposed skin |
- |
20 |
|
Non-sun-exposed skin |
- |
|
Source: Kuhn, A. (2016). S1 guideline: Cutaneous Lupus Erythematosus. Awmf.org. Retrieved 30 May 2016, from http://www.awmf.org/leitlinien/detail/ll/013-060.html
Notice!
Sun exposure and deterioration afterwards?
S. spec. diseases.
Avoid common mistakes:
Standard Dermatology USB
General measures
Topical therapies
Systemic therapy
Therapy of 1st choice according to AWMF guideline
Therapy of 2nd choice according to AWMF guideline
Therapy of 3rd choice according to AWMF guideline
Not recommended is the use of azathioprine.
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