Mammary Paget's disease

Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: 2E65.5

Morbus Paget, cancer eczema, Paget`s disease, Paget`s disease of the nipple.

Unilateral, intraepidermal, usually intraductal adenocarcinoma of the nipple.

  • Very rare in men
  • Peak in age: after 40 years

Cause is unclear.

Unsharp, erythematous, unilateral, indolent, weeping, possibly slightly scaly, centrifugally growing, partly eczematous, partly ulcerating papule or plaque in the area of the nipple. Retraction of the nipple may occur. In some cases, subcutaneous nodules are palpable

  • Clinical image
    • Any unilateral eczematous skin lesion in the region of the nipple should be biopsied.
  • Palpation
    • Breast
    • Locoregional lymph nodes
  • Staging, if indicated
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