Last Updated: 2022-03-25
Author(s): Anzengruber F., Navarini A.
Harms et al. 1990.
Glove Sock Syndrome.
Viral exanthema with skin involvement of hands, feet and mucous membranes.
- Mostly occurring in young adulthood
- Seasonal peak incidence in spring and summer
- Incubation period: 6-14 days
The syndrome is associated with parvovirus B19, coxsackie, cytomegalovirus, Epstein-Barr, measles, HIV, rubella and hepatitis B virus..
- In addition to moderately high fever, there is lymphadenopathy, arthralgia, myalgia and loss of appetite
- Multiple, pruritic, livid red papules arranged glove-like on the hands and sock-like on the feet. After 24-48 hours, there is gradual confluence of the papules and formation of oedema and oedematous erythema. Petechiae and petechial purpura may also be common. Enorally, vesicles, aphthae and erosions are visible.
- Contagiousness exists before and during the onset of exanthema
- The blood count is non-specific
- Direct pathogen detection by PCR or antigen test
- Self-limiting course
- Healing without complications after 1-2 weeks
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