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Toxic oil - Syndrome

Last Updated: 2019-08-26

Author(s): Anzengruber F., Navarini A.

ICD11: -

Tabuenca 1981

TOS, toxic szndrome

An autoimmune disease (pseudoscleroderma syndrome) caused by contaminated (acetanilide) edible oil, which occurred in Spain in 1981.

Pseudoscleroderma, contractures

Myalgia

Eosinophilia (serological)

Encephalopathy

Medical history

Clinic

Differential blood count (eosinophilia)

ANAs titre (increased in approx. 50%)

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Avoid the trigger.

PUVA therapy, if necessary

Systemic scleroderma
Morphea

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