Tetracycline

Tetracycline /Nikotinamid (=Vit. B3)

Blood count, liver values, kidney values

p.o.

Doxycycline 2x 100 mg / day and 3x 500 mg Niacinamide / day (Nicobion®)

Variable

Liver influence

Tetracycline: transaminases ≥3x upper standard values. Nausea, fever, AZ reduction: discontinuation of therapy. Pregnancy, Childhood, Retinoids (Pseudotumor cerebri)

Tetracycline: photosensitization (sunburn, involvement of nails (nail detachment), transaminase elevation, esophagitis, pseudomembranous colitis)

Not limited