Primary cutaneous intravascular large B-cell lymphoma

Pfleger and Tappeiner 1959.

Angioendotheliomatosis proliferans systemitisata.

Rare B-cell lymphoma.

• Men = women
• Peak in frequency: ≥ 60th y

Due to intravascular tumour cell infiltrates, occlusion of smaller vessels occurs.

• In the area of the legs and lower abdomen, there are few characteristic reddish, infiltrated, partly slightly bluish, partly ulcerated nodules and plaques.
• ↓ AZ, fever, B-symptomatology, neurological deficits (dementia, visual and speech disorders).

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