Chronic radiodermatitis

Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: EJ71

Radioderm, chronic radiographic dermatitis, radioderm, radiodermia.

Dermatitis triggered by chronic exposure to ionising radiation (α-, β-, γ-, radium and boundary rays)

.

High doses of radiation.

Poikiloderma, atrophic, exsiccated skin with extensive telangiectasia. Loss of skin appendages and hypo- and hyperpigmentation. Poor healing tendency.

  • Radiographic ulcer
  • Radiographic keratosis
  • Carcinoma development
.
  • Regular dermatological examinations to exclude neoplasia
  • Avoidance of trauma
  • Stage-appropriate ulcer therapy

Topical therapy

  • Topical steroids (short-term if necessary in case of pronounced inflammatory reaction)

  • Mometasone fuorate cream / solution / ointment
  • Clobetasol cream 1-2 dgl (for 1-3 days)

  • Refatting local therapy

  • Acetylsalicylic acid p.o. 500 mg 3x tgl.
  • Tramadol 20-40 drops t.gl.
  • Ibuprofen p.o. 400-800 mg tgl.
  • if needed
Therapy of 1st choice according to Lebwohl Evidence level
Prevention
Acute radiodermatitis
Refatting E
Topical glucocorticoids A
Emulsions with trolamine A
Ringelflower extract (topical) A
Dexpanthenol A
Silver sulphadiazine B
Chronic radiodermatitis
Refatting E
Therapy of the 2nd choice after Lebwohl
Silver-containing dressings (under investigation) A
Dead Sea products (under investigation) A
Amifostine B
Pentoxifylline (under investigation) A
Celecoxib (under investigation) E
Amitriptyline, Ketamine, Lidocaine Gel C

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