Chronic radiodermatitis
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: EJ71
Radioderm, chronic radiographic dermatitis, radioderm, radiodermia.
Dermatitis triggered by chronic exposure to ionising radiation (α-, β-, γ-, radium and boundary rays)
.High doses of radiation.
Poikiloderma, atrophic, exsiccated skin with extensive telangiectasia. Loss of skin appendages and hypo- and hyperpigmentation. Poor healing tendency.
- Radiographic ulcer
- Radiographic keratosis
- Carcinoma development
- Regular dermatological examinations to exclude neoplasia
- Avoidance of trauma
- Stage-appropriate ulcer therapy
Topical therapy
- Topical steroids (short-term if necessary in case of pronounced inflammatory reaction)
- Mometasone fuorate cream / solution / ointment
- Clobetasol cream 1-2 dgl (for 1-3 days)
- Refatting local therapy
- Acetylsalicylic acid p.o. 500 mg 3x tgl.
- Tramadol 20-40 drops t.gl.
- Ibuprofen p.o. 400-800 mg tgl. if needed
| Therapy of 1st choice according to Lebwohl | Evidence level |
| Prevention | |
| Acute radiodermatitis | |
| Refatting | E |
| Topical glucocorticoids | A |
| Emulsions with trolamine | A |
| Ringelflower extract (topical) | A |
| Dexpanthenol | A |
| Silver sulphadiazine | B |
| Chronic radiodermatitis | |
| Refatting | E |
| Therapy of the 2nd choice after Lebwohl | |
| Silver-containing dressings (under investigation) | A |
| Dead Sea products (under investigation) | A |
| Amifostine | B |
| Pentoxifylline (under investigation) | A |
| Celecoxib (under investigation) | E |
| Amitriptyline, Ketamine, Lidocaine Gel | C |
- Garcia Reitbock J, Feldmann R, Ruhringer K, Breier F, Steiner A. Chronic radiodermatitis following percutaneous transluminal coronary angioplasty. J Dtsch Dermatol Ges 2013;11:265-6.
- Montesu MA, Amadu V, Satta R. A case of chronic radiodermatitis after transjugular intrahepatic portosystemic shunt. J Eur Acad Dermatol Venereol 2016;30:496-7.
- Conejo-Mir JS, Moreno JC, Camacho F. Cryosurgical treatment of professional chronic radiodermatitis. Dermatol Surg 1997;23:483-6.
- Richert B, de la Brassinne M. Subungual chronic radiodermatitis. Dermatology 1993;186:290-3.
- Lebwohl, Mark. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. Elsevier, 2014. Print.
This website uses cookies!
We use cookies to tailor our content to your needs and continuously improve our website. You can decide which cookies you want to allow. Detailed information about the cookies we use can be found in our Privacy Policy and Cookie Settings. You can withdraw your consent at any time.